Small molecule inhibitors to reprogram the tumour environment and improve immunotherapy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1141847

Funding Status
Closed

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Funded Activity Summary

Cancer blood vessels are different to normal blood vessels; they help cancer cells to spread and stop immune cells in their tracks. We have identified drugs which help to make cancer blood vessels more normal and also bring immune cells into the cancer core. We will test these drugs in combination with immunotherapies, a new treatment option which has not reached its full potential in the clinic. Since our drug candidates are already in clinical use, we expect to fast track clinical development.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $784,520.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Solid Tumours

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

angiogenesis | drug effects | macrophages | signalling pathways | tumour immunotherapy

Related Links