Developmental Vitamin D-deficiency and Autism; exploration of potential mechanisms and refining phenotype in an animal model

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1141699

Funding Status
Closed

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Funded Activity Summary

We have now shown in a large cross-sectional study that low levels of vitamin D during gestation increase the incidence of autism in children. When we model this risk-relationship in animals we show changes in important developmental processes and behaviours previously linked to autism in children. We now want to understand both the exact downstream molecular pathways affected in the developing brain along with the precise brain structural and behavioural abnormalities produced in offspring.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $442,249.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

animal model | autism spectrum disorders | early brain development | maternal nutrition | vitamin D

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