Codon bias: a hidden layer of translational regulation by estrogens

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1141339

Funding Status
Closed

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Funded Activity Summary

The hormone estrogen signals through its receptors to mediate both transcription in the nucleus and signalling known to affect translation in the cytoplasm. It is currently unknown in which way the response to estrogen is orchestrated by integrating the translation of messenger RNAs with the transcription of target genes. The project aims to determine how estrogen signalling is integrated by carefully dissecting how messenger RNAs are transcribed and translated under its control.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $420,922.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA metabolism | hormone receptors | proliferation | protein synthesis | signalling pathways

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