Systems approaches to understanding the assembly of mitochondrial machines

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1140906

Funding Status
Closed

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Funded Activity Summary

Mitochondria produce the energy for our bodies. Defects in this process cause mitochondrial disease, which affects at least 1/5000 people. Diagnosis is often inconclusive as we do not understand the function of many proteins important in mitochondrial energy production. State of the art CRISPR gene-editing tools will be coupled with advanced proteomics techniques to model different types of mitochondrial disease and identify the functions of new candidate disease genes.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $600,005.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

mitochondria | mitochondrial disease | mitochondrial function | mitochondrial respiration | proteomics

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