Discovery and Characterisation of Novel Tick Evasins as Inhibitors of Chemokine-mediated Inflammation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1140867

Funding Status
Closed

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Funded Activity Summary

An important aspect of inflammatory diseases is the migration of white blood cells into the affected tissues. This is controlled by a group of proteins called chemokines. Ticks, which live on mammalian hosts, produce proteins called evasins, which interact with host chemokines and thereby prevent inflammatory responses. This project will discover new tick evasins, study their chemokine interactions and investigate their ability to block inflammation in allergic asthma.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $654,847.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

chemokines | inflammatory mediators | inhibition | protein binding | structure-function

Related Links