Systems approaches to understanding mitochondrial function and dysfunction in disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1140851

Funding Status
Closed

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Funded Activity Summary

Mitochondria produce the energy for our bodies. Defects in this process cause mitochondrial disease, which affects at least 1/4300 people. Diagnosis is often inconclusive and few if any effective treatments exist. State of the art CRISPR gene-editing tools will be used to make disease models mimicking the different types of mitochondrial disease. These will be used to understand how mitochondria function, identify new disease genes and develop new drugs.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Career Development Fellowships

Funding Amount: $431,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

membrane protein | mitochondria | mitochondrial disease | mitochondrial encephalomyopathies | respiratory chain

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