Exploring and Targeting the Anti-Inflammatory Signalling Mechanisms of Interleukin 37

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1140820

Funding Status
Closed

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Funded Activity Summary

Cytokines are messenger proteins that function as master regulators of biological processes; thus they play central roles in many diseases. The rare cytokines that block inflammation do so by dampening the immune system’s potentially destructive force, making them attractive targets for drug development. We showed that interleukin 37 is a powerful anti-inflammatory cytokine, and will now evaluate its mechanisms of action and its efficacy against several severe diseases, including cancer.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $1,018,306.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory | cytokine signalling | cytokine therapy | monocyte/macrophage | transcriptional regulation

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