How caveolae condition tissue mechanics for an anti-tumor niche.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1140090

Funding Status
Closed

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Funded Activity Summary

The outcome of cancer is determined not only by the behaviour of the cancer cell, but also by how the normal tissue cells of the body respond to it. This project investigates how tissue cells that surround cancer cells can eliminate early cancers from the body. It develops on newly-discovered mechanisms that allow epithelial tissues to detect and physically expel cancer cells. This mechanism can protect us from cancer, but potentially allow cancer to develop when it fails.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $1,091,226.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adhesion mechanisms | cancer biology | caveolae | cytoskeleton | epithelial biology

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