Targeting inflammation as a biomarker and treatment for Alzheimer's disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1139469

Funding Status
Closed

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Funded Activity Summary

We are undertaking the challenge of using and developing novel animal models in parallel with studies on affected human subjects to elucidate the underlying molecular mechanisms linking the changes in inflammation to amyloid plaques, neurofibrillary tangles and cognitive decline. Understanding these mechanisms will allow us to define the biological pathways involved in the onset and progression of Alzheimer’s disease, and identify potential biomarkers and therapeutic targets.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Targeted Calls

Funding Amount: $718,920.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | apolipoprotein E | astrocytes | inflammation | interleukins (IL)

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