Studies on the pathogenesis of human pterygia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/113905

Funding Status
Closed

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Funded Activity Summary

Pterygia, one of the most common ocular complaints in Australia and worldwide, are thought to originate from overexposure to UV light. We propose that UV-irradiation stimulate certain cells in the eye to produce cytokines, growth factors and enzymes which degrade scaffold proteins such as collagens. These enzymes may play a key role in the progressive and invasive nature of pterygia. Dissecting the mechanism(s) by which UV light induces these proteins will lead to new and more reliable therapies for the treatment of pterygia.

Funded Activity Details

Start Date: 01-01-2000

End Date: 01-01-2002

Funding Scheme: NHMRC Project Grants

Funding Amount: $204,972.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Opthalmology And Vision Science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cornea, Conjunctiva, Limbus | Cytokines | Growth factors | Matrix metalloproteinases | UV-irradiation | blindness | disease recurrance | eye surgery | solar eye disease

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