Interleukin 37 – a Novel Cytokine Therapy for Necrotizing Enterocolitis in the Preterm

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1138926

Funding Status
Closed

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Funded Activity Summary

Neonatologists are adept at keeping extremely premature babies alive. But the price is a rising incidence of life-threatening diseases that include necrotising enterocolitis (NEC), a progressive and destructive intestinal inflammation that may require surgery, after which just 30% survive. We have created highly potent variants of the anti-inflammatory molecule interleukin 37 whose actions will improve our understanding of NEC pathogenesis and reveal their therapeutic potential in NEC.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $748,848.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Paediatrics and Reproductive Medicine not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cytokine therapy | gut immunity | immune regulation | inflammatory diseases | intestine

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