How do you SNARE a synaptic vesicle?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1138083

Funding Status
Closed

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Funded Activity Summary

The neuronal synapse is very tightly regulated by proteins that control both the timing and the amount of neurotransmitter release and neuronal stimulation. Defects in this synaptic signal are linked to diseases including epilepsy, autism and dementia. In this study we will determine the molecular details of how proteins called SNAREs control neurotransmission in the human brain.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $654,428.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

mammalian homologue of the unc-18 gene (Munc-18) | membrane fusion | molecular imaging | soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) | synaptic mechanisms

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