Understanding the biological mechanisms involved in treatment free remission of chronic myeloid leukaemia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1138079

Funding Status
Closed

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Funded Activity Summary

Most patients with chronic myeloid leukaemia achieve excellent responses to therapy but need therapy for life. We have pioneered the concept that some patients can cease their therapy and not relapse (treatment free remission –TFR). By studying the immune system, the leukaemic stem cells and the bone marrow environment, we will determine why TFR is possible for some, but not all patients. This holds the key to improving the rate of TFR, thus moving the CML goal from disease control to cure.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Early Career Fellowships

Funding Amount: $318,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Therapy (excl. Chemotherapy and Radiation Therapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone marrow stroma | immune function | myeloid leukaemia | relapse prevention | stem cell biology

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