Mechanobiology of epithelial homeostasis in health and disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1136592

Funding Status
Closed

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Funded Activity Summary

Epithelial tissues, such as the lung, fundamentally protect the body from its external environment. For this, they must detect and respond to danger. My work has discovered a new biological system where cells monitor changes in mechanical forces as a sign of danger. Diseases such as inflammation and cancer occur when this detection system fails. This Fellowship builds on my lab’s pioneering work to understand how force is used to sense danger, and how disease occurs when it goes awry.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2022

Funding Scheme: Research Fellowships

Funding Amount: $876,005.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adhesion mechanisms | cell signalling | cytoskeleton | epithelium | inflammation

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