Determining the mechanisms of tolerance after autologous stem cell transplantation for Multiple Sclerosis – the role of CD39+ T regulatory cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1132822

Funding Status
Closed

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Funded Activity Summary

Autologous haematopoietic stem cell transplant offers relief for patients with aggressive forms of autoimmune diseases such as multiple sclerosis. Here, we aim to understand how this therapy relieves symptoms in multiple sclerosis patients by studying the biology of CD39+ T regulatory cells. Understanding these immune-suppressing cells can lead to the development of new transplant procedures without chemotherapy and ultimately improve transplant outcomes for autoimmune disease patients.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Postgraduate Scholarships

Funding Amount: $86,117.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cells | autoimmune disease | clinical trial | multiple sclerosis (MS) | transplantation biology

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