Exercise reverses cognitive decline in aged animals by growth hormone stimulation of neurogenesis in the hippocampus

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1130141

Funding Status
Closed

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Funded Activity Summary

The production of new neurons in the hippocampus plays a critical role in learning and memory. With increasing age, this production slows and is associated with cognitive decline. However the stem cells that make new neurons are still present, and we have discovered that exercise activates these cells, leading to renewed neuron production and reversal of cognitive decline. We will explore how this process is regulated in order to develop strategies to reduce cognitive decline in humans.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $696,409.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

exercise therapy | growth hormone | learning deficits | neurogenesis | stem cells

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