Transcriptional regulation of definitive hematopoietic development in humans

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1129861

Funding Status
Closed

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Funded Activity Summary

Blood stem cell transplantation is a vital therapy for patients with leukaemia following chemotherapy or for patients with bone marrow failure. Because many patients lack a donor, there is a need for an alternate source of stem cells, such as human pluripotent stem cells. During development, blood cells are formed from the blood vessel wall, or endothelium. In this project, we will study the regulation of this process in order to more efficiently make human blood cells in the laboratory.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $800,036.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

developmental biology | embryonic stem cells | endothelium | haematopoiesis | haematopoietic stem cells

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