Reversing the biomechanical dysregulation of cancer cell signalling to improve targeted therapies

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1129766

Funding Status
Closed

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Funded Activity Summary

The limited success of cancer drugs is dependent on many factors including the physical properties (stiffness) of a tumour. In particular whether a tumour is soft or stiff affects how it responds to treatment. Combining classical biology with engineering to generate 3D models that mimic tumours, along with cutting-edge imaging technology, we will determine how we can target the physical properties of tumours together with already approved cancer drugs to improve treatment and patient outcome.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $663,447.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biomechanics | breast cancer | colon cancer | extracellular matrix | targeted therapy

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