Epigenetic mechanisms of dysregulated immune function in autoimmune and allergic disease of childhood

Funding Activity

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Funded Activity Summary

The rising incidence of autoimmune and allergic diseases is ascribed to the environment, which can modify the chemistry of DNA and how our genes work (epigenetics). We aim to identify epigenetic changes in immune cells in infants at risk for type 1 diabetes and food allergy followed from birth. This may reveal both general and disease-specific levels of epigenetic-immune dysregulation and is a foundation on which to understand potentially modifiable environment-gene interactions.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $452,298.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

child health | epigenetics | food allergy | immunology | type 1 diabetes mellitus (insulin-dependent diabetes mellitus)