Tuberous sclerosis and epilepsy: using resected tissue to understand pathogenesis and inform management

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1128933

Funding Status
Closed

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Funded Activity Summary

Epilepsy is the commonest neurological disorder in childhood and seizures cannot be fully controlled by medications in 30%, often leading to developmental consequences. A major cause of drug-resistant epilepsy is a malformation of the brain’s surface. Surgery is sometimes used to remove these lesions to treat the epilepsy. We will study this tissue to understand its architecture, genetic basis and how it causes seizures. Our results will guide treatment including the best surgical approach.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $339,261.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

brain abnormalities | congenital brain defects | epilepsy | epilepsy surgery | neurogenetics

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