Validation of PAG1 as a new risk gene with therapeutic potential for asthma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1128493

Funding Status
Closed

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Funded Activity Summary

About 10% of adults and children suffer from asthma in Australia. For >60% of these their asthma symptoms are not well controlled with existing treatments and so novel therapies are needed. We have recently identified PAG1 as a novel risk gene for asthma. In this study, we will conduct mouse and human studies to investigate the possibility inhibition of PAG1 might help prevent or treat asthma exacerbations.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $687,436.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetics not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

asthma | gene discovery | immune function | inflammatory diseases | mouse models

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