Epithelial metabolism as a mediator of host-microbiome interactions in inflammatory bowel disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1128487

Funding Status
Closed

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Funded Activity Summary

This project examines how the changes in the intestinal environment during inflammation influences the behaviour of bacteria within the micobiome and whether those changes can be counteracted to sustain a healthy microbiome, even during episodes of disease. This work uses cell and animal models to examine how inflammation changes the intestinal nutrients that the microbiome requires to maintain its community and whether supplementing the microbiome with these nutrients can prevent disease.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $833,648.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bacterial pathogenesis | host/pathogen interaction | hypoxia | inflammatory bowel disease (IBD) | mucosal inflammation

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