Radiosensitisation of diffuse intrinsic pontine gliomas by modulating glucose metabolism

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1128483

Funding Status
Closed

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Funded Activity Summary

Diffuse intrinsic pontine glioma (DIPG) represents the most aggressive cancer of childhood with no effective treatment available and radiotherapy is the only form of treatment that offers a transient benefit. We have successfully grown the first DIPG cells in the laboratory and found a new approach to radiosensitise them by targeting glucose metabolism. We will build on these findings and develop this treatment strategy to make this novel therapy available to children with this deadly disease.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $325,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Radiation Therapy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

brainstem | glioma | glucose metabolism | radiation therapy | translational research

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