Hormone Transport by Alpha-2-Macroglobulin: Novel Roles in Regulating Hormone Activity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1128152

Funding Status
Closed

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Funded Activity Summary

Alpha-2-macroglobulin is a large protein in the blood known to bind and transport numerous hormones in the circulation. Our previous studies published in BLOOD (2009) and JBC (2013) have discovered an important role for this molecule in the transport and regulation of a peptide hormone. The studies proposed in this application have important implications for understanding new roles of alpha-2-macroglobulin in hormone binding and regulating the activity of hormones in disease states.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $602,857.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

hormone action | hormone receptors | hormone signalling | hormones | protein binding

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