TAU AND ITS MASTER REGULATOR FYN IN NEURONS

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1127999

Funding Status
Closed

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Funded Activity Summary

Neurons are highly compartmentalized cell-types. In neurodegenerative diseases such as Alzheimer's disease, the protein Tau that serves a distinct function in one cellular compartment (the axon) accumulates in a massively phosphorylated form elsewhere (somatodendritic compartments and their spines) which is believed to impair neuronal functions. We will investigate how Tau is distributed in health and disease, and determine how this distribution is regulated.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $758,742.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

axonal transport | dendrites | microtubule associated protein (MAP) | synapse | tyrosine kinase

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