(Re)wiring a stem cell: Deciphering the molecular mechanism underpinning lineage propensity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1127976

Funding Status
Closed

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Funded Activity Summary

This project explores the response of the stem cells to cues that direct how they turn into specific type of cells that is suitable for clinical use. Specifically, a set of driver genes whose activity can foretell the outcome of cell differentiation will be identified. By modulating the maintenance conditions, iPSCs lines may be tailored for specific applications in stem cell therapy and disease modelling for the assessment of treatment efficacy.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $855,780.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell differentiation | gene regulation | signalling pathways | stem cell biology | stem cell therapy

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