Pacing across the membrane: Characterising the PACE family of multidrug efflux systems

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1127615

Funding Status
Closed

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Funded Activity Summary

The World Health Organisation recognises bacterial antimicrobial resistance as one of the major threats to human health worldwide. Multidrug efflux pumps are an important class of resistance proteins that sit in the bacterial cell membrane and move antimicrobials out of the cell. We recently discovered the first new family of multidrug efflux pumps to be described in 15 years. Our project will define the precise resistance functions of this family and identify ways to block their function.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $640,815.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

drug transport | molecular microbiology | multidrug resistance | pathogenic bacteria | transporters

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