Characterisation of Anti-HBs Responses in Patients Undergoing Functional Hepatitis B Cure: Implication for Future Therapies

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1127538

Funding Status
Closed

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Funded Activity Summary

The hepatitis B virus causes liver cirrhosis and liver cancer. There is no cure for hepatitis B. However, a small number of patients can naturally rid themselves of the virus. We have identified 14 of these individuals and discovered that they have a unique immune response that is responsible for these “natural” cures. We plan to characterise this immune response and turn it into a therapeutic vaccine which can be used to cure patients who are still chronically infected.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $723,649.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibody therapy | hepatitis B infection | hepatitis B virus | vaccine design | vaccine technology

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