A study of the plaque-modifying actions of colchicine in stable and unstable atherosclerosis: from mouse models to clinical imaging.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1127159

Funding Status
Closed

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Funded Activity Summary

Inflammation causes the plaques in arteries that cause heart attacks and strokes. There is major interest in developing drugs that reduce this inflammation for patients with heart disease. We are studying the effects of colchicine, an anti-inflammatory drug used to treat the joint disease, gout, in order to see whether it also prevents the build up of plaques and their progression to heart attacks and strokes.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $1,198,460.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atherosclerosis | coronary artery disease | drug therapy | inflammation | plaque rupture

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