Delineating aberrant adaptive immune responses due to germline mutations in the PI3K signalling pathway

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1127157

Funding Status
Closed

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Funded Activity Summary

Activation of immune cells is required to generate appropriate immune responses that protect is from disease caused by pathogens. The inability to receive the correct type of signals causes immunodeficiency. The PI3 kinase pathway is central to immune cell activation – and genetic errors in this pathwat compromise the functioning of immune cells. We will investigate the nature of these defects and pursue avenues of overcoming them using pharmacological inhibitors of the PI3K pathway.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $975,476.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cellular immunology | humoral immunology | immunodeficiency | immunologic disease | immunologic memory

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