Exploring the role of matrix metalloproteinase 12 (MMP12) in macrophages during bacterial infection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1126842

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Golden staph infections incur a high morbidity and mortality in Australia costing AUD150M p.a. One of our strongest lines of defense, white blood cells, are known to secrete an extracellular enzyme, matrix metalloproteinase 12 (MMP12). MMP12 digests and modifies functions of other proteins. We will utilize unbiased large-scale “omics” technologies to identify genes responsible for infection dampening due to MMP12 function. This will allow for better informed drug design to treat superbugs.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Early Career Fellowships

Funding Amount: $384,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

infection | macrophages | matrix metalloproteinases | proteomics | systems biology

Related Links