Neurodevelopmental outcome after sevoflurane versus dexmedetomidine/remifentanil anaesthesia in infancy: a randomised controlled trial

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1126535

Funding Status
Closed

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Funded Activity Summary

Evidence in animals show that some anaesthetics affect the developing brain. Some human data also show a link between childhood surgery and poorer neurodevelopmental outcome. It is unknown if this association is due to the anaesthetic. Our recent GAS trial showed no evidence for toxicity after 1 hour of anaesthesic but many children have longer anaesthetics. We plan to enrol 420 infants in a study comparing neurodevelopmental outcome after 2 different anaesthetics for surgery lasting >2 hours.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $825,787.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Anaesthesiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anaesthesia | developmental outcomes | neurodevelopment | paediatric | randomised controlled trial (RCT)

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