Structure-function of type I interferon receptors: informing the basis for selective modulation of signal transduction and function

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1126524

Funding Status
Closed

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Funded Activity Summary

Interferons (IFNs) are a family of proteins with critical roles in infectious and inflammatory diseases and cancers. Currently we do not understand why there are so many type I IFNs, their different functions and how they are achieved. This project will determine at a fine molecular level how different IFNs interact with molecules on target cells and transmit particular signals. We will focus on a novel IFN? that we discovered. These studies will underpin the development of new therapies.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $1,316,153.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

inflammatory diseases | innate immunity | interferon (IFN) | signalling pathways | structure-function

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