The role of NADPH oxidase-Nox5 in diabetic kidney disease: in vitro and in vivo studies

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1126169

Funding Status
Closed

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Funded Activity Summary

Diabetes related kidney disease is the leading cause of kidney failure. Individuals with this disorder often require dialysis or transplantation. Our current treatment strategies fail to prevent or cure this disorder. Thus, novel treatments are urgently needed. In the present study, I will investigate the role of the pro-oxidant enzyme Nox5 in the kidney damage seen in diabetes by using a mouse model of diabetic kidney disease and will validate Nox5 as promising targets for the treatment of DN.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Early Career Fellowships

Funding Amount: $318,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

diabetic nephropathy | fibrosis | nicotinamide adenine dinucleotide phosphate (NADPH) oxidase | oxidative stress | reactive oxygen species (ROS)

Related Links

ACN 633 798 857