Studies into Myeloperoxidase-Induced Cardiovascular Disease and its Treatment

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1125392

Funding Status
Closed

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Funded Activity Summary

During cardiovascular disease an inflammatory protein called myeloperoxidase (MPO) becomes abnormally released into the circulating blood and is transported into diseased blood vessels. Our studies show for the first time that increasing circulating levels of MPO promotes both atherosclerosis and aortic aneurysm. This project will study how MPO promotes inflammatory artery disease and test new drugs for their ability to inhibit this damaging protein and protect against cardiovascular disease.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $924,596.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

abdominal aortic aneurysm | atherosclerosis | myeloperoxidase | oxidative stress | pharmacological intervention

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