Identification of E-protein complexes controlling natural killer cell fate and tumour immunity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1124907

Funding Status
Closed

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Funded Activity Summary

Diverse immune cell types are essential for effective broad-spectrum immunity. Master regulators control this diversity and have a well-characterized role in the development of antigen-specific immunity. In contrast, we lack mechanistic understanding of how master regulators control antigen-unspecific, innate immunity. Understanding the mechanism behind this will explain how diverse white blood cells can develop and reveal strategies to skew their development to improve immunity in humans.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $683,742.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

interleukins (IL) | lymphocyte differentiation | natural killer cells | transcriptional regulation | tumour immunology

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