Prevention of HIV-1 infection by adeno associated virus vector-delivered broadly neutralizing antibodies or antibody-like molecules

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1124680

Funding Status
Closed

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Funded Activity Summary

A promising neutralizing molecule has boosted hopes of an HIV vaccine. It remains unknown how well this molecule prevents HIV infection under conditions reflecting “real world” exposure, including exposure to HIV in the form of cells carrying virus or free-floating virus in the presence of semen. We will assess this molecule for their ability to inhibit transmission of HIV-like viruses under these conditions. These experiments will define requirements to protect against HIV infection.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $875,854.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Fc receptors | acquired immunodeficiency syndrome (AIDS) | antibody | human immunodeficiency virus (HIV) | primate

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