Regulating microglia to combat hippocampal-dependent cognitive decline in ageing

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1124503

Funding Status
Closed

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Funded Activity Summary

Age-related cognitive decline, a hallmark of dementia, coincides with reduced activity of neural precursor cells and reduced rate of neuron production in the hippocampus – a key brain structure for learning and memory. Importantly, we have demonstrated that exercise can activate neural precursor cells and boost the production of new neurons as well as improve learning and memory. This project will explore the cellular and molecular mechanisms behind these exercise-induced benefits on cognition.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $493,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ageing | cognition | hippocampus | microglia | neurogenesis

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