Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1124474

Funding Status
Closed

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Funded Activity Summary

There is no cure for DMD, a devastating, life-limiting muscle disease causing progressive muscle wasting in boys and young men. A potential therapy may come from modulating muscle activity patterns to promote a protective slow muscle phenotype through low-frequency stimulation protocols and/or well-described pharmacological ‘exercise mimetics’. This proposal will evaluate their therapeutic merit in mouse models of DMD to answer the key questions to advance this approach to the clinic.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $780,476.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Physiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

muscle damage | muscle fibre types | muscle metabolism | muscle regeneration | muscular dystrophy

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