Analysis of human CD4+ T-cell responses to epitopes formed by peptide fusion in the pathogenesis of type 1 diabetes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1123586

Funding Status
Closed

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Funded Activity Summary

Type 1 diabetes is caused by immune-mediated destruction of the insulin-secreting beta cells. Recently we discovered new targets ‘seen’ by the immune system that may explain why the immune system causes type 1 diabetes. Here we will determine if responses to these targets cause type 1 diabetes. This is important because it tests a new idea and our results will have a major impact on efforts to develop new therapies for type 1 diabetes an other autoimmune diseases.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $1,239,989.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antigen | autoimmunity | human leukocyte antigen (HLA) | immune function | type 1 diabetes mellitus (insulin-dependent diabetes mellitus)

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