Self-destructing CRISPR-constructs for targeted genome editing in the retina.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1123329

Funding Status
Closed

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Funded Activity Summary

Despite the identification of specific mutations causing many inherited retinal dystrophies, all of these conditions are currently untreatable. We have established gene-editing techniques and have developed a novel mouse model, which will serve as a robust platform for testing different techniques of gene editing in the retina. No other group in the world is known to be using this platform for gene editing and our work will expedite the clinical translation of this technology.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $679,926.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene and Molecular Therapy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

blindness | gene mutations | gene targeting | genetic engineering | retinal dystrophy

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