Pathophysiology, site of disease onset and mechanisms of spread in amyotrophic lateral sclerosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1123026

Funding Status
Closed

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Funded Activity Summary

Amyotrophic lateral sclerosis (ALS) is a fatal disease of the human motor system resulting in progressive paralysis of voluntary muscles and death within 5 years of symptom onset. A key unresolved issue in the understanding of where ALS starts and what factors drive the disease. This project will utilise sophisticated techniques to determine the site of onset, factors controlling disease spread and ultimately identify treatment targets that could slow down or even stop disease progression.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $704,270.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

amyotrophic lateral sclerosis | cortex | excitability | motor neuron disease (MND) | neurodegenerative disorders

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