The JAK/STAT pathway in health and disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1122999

Funding Status
Closed

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Funded Activity Summary

A number of Leukemias, lymphomas and other blood malignancies are caused by mutations in a protein called JAK (Janus Kinase). To combat this human cells produce a protein that inhibits JAK (called SOCS). We aim to study how this process works and to mimic SOCS with a drug in order to treat leukemia.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $866,656.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

JAK/STAT pathway | cytokine signalling | structural biology | structure-based drug design | structure-function

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