Understanding the cause of muscle weakness in Nemaline myopathy (NM) – moving towards the development of targeted treatments

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1121651

Funding Status
Closed

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Funded Activity Summary

Congenital myopathy patients have unremitting, life-long muscle weakness that severely affects their quality of life and ability to perform normal daily activities. Currently no effective therapies exist for these conditions, largely due to our limited understanding of the mechanisms leading to muscle weakness. This ECF aims to determine the cause of weakness and test two therapies which have shown promise for other conditions and can be translated into clinical use for myopathies if effective.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Early Career Fellowships

Funding Amount: $408,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

actin | genetic disorders | muscle contraction | myopathy | physiology

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