Genome-wide analysis of gene regulatory networks in heart development and congenital heart disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1121172

Funding Status
Closed

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Funded Activity Summary

Despite advances in surgical methods and hospital critical care, congenital heart disease (CHD) remains the leading cause of non-infectious death in children in the first year of life. Severe CHD requires multiple surgeries and a lifetime of emotional and financial burden. In this proposal we will use new molecular and genetic approaches to ask how the network of genes that normally participates in heart development is controlled by regulatory factors, and how the network is disturbed in CHD.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $1,263,954.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure and Regulation

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

developmental biology | heart development | heart disease | mouse models | transcription factor

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