Improving cancer diagnostic imaging and drug delivery by breaking down extracellular matrix barriers

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1121131

Funding Status
Closed

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Funded Activity Summary

Solid tumours are stiffer than normal tissues. This stiffness is caused by over-production of non-cellular components known as extracellular matrix (ECM). ECM creates a barrier that restricts drug access in tumours. New methods to overcome tumour stiffness are crucial to improve drug delivery. We will study the use of a new compound to degrade tumour ECM to improve anti-cancer drug delivery. Our compound will be useful in treatment-resistant solid tumours such as breast and liver cancers.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $748,152.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Solid Tumours

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

extracellular matrix | imaging | immune-mediated | nanotechnology | therapy

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