Protecting the efficacy of antimalarial therapies with novel approaches to suppress the emergence of drug resistance

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1120690

Funding Status
Closed

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Funded Activity Summary

The global campaign to eliminate malaria is under serious threat from the continuing emergence and spread of Plasmodium falciparum parasites resistant to antimalarial drugs. However in acquiring resistance to one drug, the parasite can become more susceptible to other antimalarials. This project aims to 1) test the ability of drug pairs with opposing selection forces to suppress resistance in vitro and 2) define the physiological and molecular basis of these opposing evolutionary forces.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2021

Funding Scheme: Early Career Fellowships

Funding Amount: $408,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Plasmodium falciparum | drug resistance | evolution | parasitology | transporters

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