Identification of the conformation dependant targets of autoimmune disease linked variation in human regulatory T cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1120543

Funding Status
Closed

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Funded Activity Summary

Specialised immune cells called regulatory T cells act as the policemen of the immune system, preventing the immune system attacking itself, but still fighting infections. If these cells do not work properly, autoimmune diseases such as type 1 diabetes or IBD can arise, because of immune attack on normal body tissue by mistake. In order to explain how this goes wrong we need to carefully identify all of the gene interactions in these cells including interactions over long distances in the DNA.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $1,001,815.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunogenetics (incl. Genetic Immunology)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

autoimmune disease | chromatin structure | enhancer elements | gene regulation | transcriptional regulation

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