Identification of New Mechanisms in Insulin Resistance

Funding Activity

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Funded Activity Summary

Type II diabetes is a major cause of disease in Australia. Resistance of the liver to the effects of insulin plays a key role in the uncontrolled blood glucose levels in this disease. In this proposal, we will combine state-of-the-art protein chemistry techniques with advanced statistical analysis to identify the pathways driving liver insulin resistance. We will also predict clinically-approved drugs that may reverse these changes, to guide drug development for future therapeutic gain.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $478,781.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

data mining | insulin resistance | mass spectrometry | protein-protein interaction | signal transduction