Unravelling the mechanism coupling synaptic activity with neurotrophin signaling in the nervous system

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1120381

Funding Status
Closed

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Funded Activity Summary

Although active brain cells are known to survive for much longer than inactive ones, the mechanism underpinning this essential process has remained elusive. We have uncovered a direct coupling between neuronal activity and survival signals. The purpose of this grant application is to establish the molecular mechanism underpinning this coupling and understand how neuropathic pathogens manage to harness it with devastating effects to the brain.

Funded Activity Details

Start Date: 01-01-2017

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $640,815.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

axonal transport | neurotrophins | retrograde transport | survival | trafficking

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